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Nucleotides & Nucleosides

Nucleotides by Structure

Fluorescent Nucleotides

Adenosines – Dye-labeled

8-[(6-Amino)hexyl]-amino-cAMP

N⁶-(6-Amino)hexyl-ADP

N⁶-(6-Amino)hexyl-ATP

8-[(6-Amino)hexyl]-amino-ATP

8-[(4-Amino)butyl]-amino-ADP

8-[(4-Amino)butyl]-amino-ATP

8-[(6-Amino)hexyl]-amino-adenosine-2'/5'-bisphosphate

8-[(6-Amino)hexyl]-amino-adenosine-3'/5'-bisphosphate

N⁶-(6-Amino)hexyl-dATP

7-Propargylamino-7-deaza-dATP

7-Propargylamino-7-deaza-ddATP

EDA-AppNHp (EDA-AMPPNP)

γ-[(6-Amino)hexyl]-N⁶-Benzyl-ATP

γ-[(6-Amino)hexyl]-ATP

γ-[(6-Aminohexyl)-imido]-ATP

γ-[(6-Amino)hexyl]-dATP

γ-[(6-Aminohexyl)-imido]-dATP

γ-[(6-Amino)hexyl]-AppCp

γ-[(6-Aminohexyl)-imido]-ATPαS

Adenosines – Quencher-labeled

8-[(6-Amino)hexyl]-amino-cAMP

N⁶-(6-Amino)hexyl-ATP

8-[(6-Amino)hexyl]-amino-ATP

8-[(6-Amino)hexyl]-amino-adenosine-2'/5'-bisphosphate

8-[(6-Amino)hexyl]-amino-adenosine-3'/5'-bisphosphate

N⁶-(6-Amino)hexyl-dATP

7-Propargylamino-7-deaza-dATP

7-Propargylamino-7-deaza-ddATP

EDA-AppNHp (EDA-AMPPNP)

γ-[(6-Amino)hexyl]-ATP

Adenosines – Intrinsically Fluorescent

Guanosines – Dye-labeled

8-[(6-Amino)hexyl]-amino-GMP

8-[(6-Amino)hexyl]-amino-cGMP

8-[(6-Amino)hexyl]-amino-GTP

7-Propargylamino-7-deaza-dGTP

7-Propargylamino-7-deaza-ddGTP

EDA-GppNHp (EDA-GMPPNP)

γ-[(4-Aminobutyl)triazolo]-GTP

γ-[(6-Aminohexyl)triazolo]-GTP

γ-[(6-Amino)hexyl]-GTP

γ-[(6-Amino)hexyl]-dGTP

γ-[(6-Aminohexyl)imido]-dGTP

Guanosines – Quencher-labeled

8-[(6-Amino)hexyl]-amino-GMP

8-[(6-Amino)hexyl]-amino-cGMP

8-[(6-Amino)hexyl]-amino-GTP

7-Propargylamino-7-deaza-dGTP

7-Propargylamino-7-deaza-ddGTP

γ-[(6-Amino)hexyl]-GTP

γ-[(6-Amino)hexyl]-dGTP

Guanosines – Intrinsically Fluorescent

Cytosines – Dye-labeled

5-Propargylamino-CTP

5-Propargylamino-dCTP

5-Propargylamino-ddCTP

pCp

Cytosines – Quencher-labeled

5-Propargylamino-CTP

5-Propargylamino-dCTP

5-Propargylamino-ddCTP

Cytosines – Intrinsically Fluorescent

Uridines – Dye-labeled

Aminoallyl-dUTP

5-Propargylamino-ddUTP

Uridines – Quencher-labeled

Aminoallyl-dUTP

5-Propargylamino-ddUTP

Uridines – Intrinsically Fluorescent

Xanthosines and Inosines – Intrinsically Fluorescent

Nucleotide Probes Trove

Non-hydrolyzable Nucleotides

α-Phosphate modified Nucleotides

Adenosine Nucleotides

Guanosine Nucleotides

Uridine Nucleotides

Cytidine Nucleotides

Thymidine Nucleotides

γ-[(6-Aminohexyl)-imido]-ATPαS

α,β non-hydrolyzable Nucleotides

Adenosine Nucleotides

Guanosine Nucleotides

Uridine Nucleotides

Cytidine Nucleotides

Thymidine Nucleotides

β-Phosphate modified Nucleotides

Adenosine Nucleotides

Guanosine Nucleotides

Uridine Nucleotides

β,γ non-hydrolyzable Nucleotides

Adenosine Nucleotides

Guanosine Nucleotides

Xanthosine Nucleotides

Inosine Nucleotides

Uridine Nucleotides

Cytosine Nucleotides

Thymidine Nucleotides

γ-Phosphate modified Nucleotides

Adenosine Nucleotides

Guanosine Nucleotides

Xanthosine Nucleotides

Inosine Nucleotides

Uridine Nucleotides

Non-hydrolyzable Di-Nucleotides

Non-hydrolyzable Nucleotide Kits

Non-hydrolyzable dye-labeled Nucleotides

γ-[(6-Aminohexyl)-imido]-ATPαS

γ-[(6-Amino)hexyl]-AppCp

EDA-GppNHp (EDA-GMPPNP)

Nucleotides labeled with...

DNP (Dinitrophenol)

Photo-labile groups ("Caged")

Triple bonds (Alkyne)

DBCO

TCO

Free amino group (-NH₂)

Halogen atoms (F, Cl, Br, I)

Methyl group (-CH₃)

Analogs and Derivatives of...

Cap

Coenzyme A (CoA)

NAD

Natural RNA Nucleobases

Unmodified (natural) Nucleotides

Single Solutions

NTPs

Single Solutions and Bundles

NDPs

RNA Dinucleotides

Important Structure Motifs

Cyclic-di-Nucleotides

3',5'-Cyclic Nucleotides

2',3'-Cyclic Nucleotides

Dinucleoside Polyphosphates

7-Deaza Purines

7-Methyl Guanosines

Substituted Pyrimidines

4-Substituted Cytidines

2-Thio Uridines

4-Thio Uridines

5-Methyl Cytidines and related

Modified ddNTPs

Biotin-labeled ddNTPs

Amine-labeled ddNTPs

Other Dideoxynucleotides

2'-Fluoro-2'-NTPs

2'-O-Methyl-NTPs

cleavable Base labeled dNTP's

Nucleotide Trove

N¹-Modified Purines

N⁶-Modified Purines

6-Modified Purines

8-Oxo Guanosines

2'-Deoxy Uridines

3'-Deoxy Nucleotides

Nucleoside Bisphosphates

ara-Nucleotides

Unmodified Purines

Other modified dNTPs

3'-O-Azidomethyl-dNTPs

3'-Phosphate-dNTPs

Adenosine Nucleotides

Guanosine Nucleotides

Cytidine Nucleotides

Uridine Nucleotides

Nucleotides by Application

Reversible termination Sequencing

Single molecule real time (SMRT) Sequencing

Chain termination Sequencing

Resolution enhancing Nucleotides

SNP Genotyping by Fragment Analysis

De novo enzymatic DNA oligonucleotide synthesis

in vitro Synthesis

Structure determination by NMR

... on Proteins/Enzymes

Probes for Protein Kinases and Protein Phosphatases

Co-translational Protein Labeling

Kinase Signaling

Non-radioactive Protein Phosphorylation Analysis

Kinase Inhibition by Di-Nucleoside Phosphates

G-Protein Signaling

Tubulin Assembling

Structural Biology

Mercurated Nucleotides

Selenium-containing Nucleotides

Non-hydrolyzable Nucleotides

α-Phosphate modified Nucleotides

α,β non-hydrolyzable Nucleotides

β-Phosphate modified Nucleotides

β,γ non-hydrolyzable Nucleotides

γ-Phosphate modified Nucleotides

Non-hydrolyzable Di-Nucleotides

Non-hydrolyzable Nucleotide Kits

ADP-Ribosylation

Nucleotide Binding Probes

Probes for ATP binding proteins

Probes for GTP Binding Proteins

... in Cell Biology

Cell Cycle & Proliferation

Apoptosis (TUNEL assay)

Protein-DNA/-RNA interaction (EMSA)

... in Signal Transduction

Ligands for P2 Receptors

P2Y₁

P2Y₂

P2Y₄

P2Y₆

P2Y₁₁

P2Y₁₂

P2Y₁₃

P2Y₁₄

P2X₁

P2X₂

P2X₃

P2X₄

P2X₅

P2X₆

P2X₇

Bacterial Second Messenger

... in Drug Discovery

SELEX/Aptamer Modification

mRNA Modification

Antiviral Nucleotides

Cytostatic Nucleotides

... for Click Chemistry

Alkyne-containing Nucleotides

DBCO-containing Nucleotides

Nucleotide Azides

TCO-containing Nucleotides

Vinyl-containing Nucleotides

... as ¹⁹F-NMR probes

Fluorescence-Based Alkaline Phosphatase-Coupled Polymerase Assay (FAPA)

Nucleosides by Structure

Unprotected Nucleosides

Unprotected Ribo-nucleosides

Thio

Unprotected 2'-Deoxy-nucleosides

DBCO

Unprotected 3'-Deoxy-nucleosides

5'-Fluorosulfonylbenzoyl-modified

Nucleosides by Application

Cancer and Proliferation Marker Nucleosides

...on Proteins/Enzymes - Sulfonyl Fluoride Probes

Stable Isotope labeled Nucleosides & Nucleotides

Immobilized Nucleotides for Affinity Chromatography

Custom Synthesis

Molecular Biology

Single Components

Polymerases & Enzymes

Lyo-ready Components

Buffer & Supplements

Polymerases & Core Kits

Log Scale DNA Ladders

Linear Scale DNA Ladders

Fluorescent Log Scale DNA Ladders

Fluorescent Linear Scale DNA Ladders

Classic DNA Ladders

Direct Amplification

TaqMan® Detection & Multiplex

SYBR®Green Detection

Dual Labeled Probes

BBQ®-650 Quencher

ECLIPSE Quencher

DABCYL Quencher

Reverse Transcription & RT-PCR

Direct Amplification

TaqMan® Detection

SYBR®Green Detection

Components and Classics

Dual Labeled Probes and Oligos

Random and Oligo (dT) Primers

BBQ®-650 Quencher

ECLIPSE Quencher

DABCYL Quencher

Isothermal Amplification & LAMP

LAMP Master Mixes

Isothermal Assays

RNA/DNA Preparation & Cleanup

Genomic DNA - Column Kits

Genomic DNA - Solution Kits

Plasmid DNA - Column Kit

Viral DNA & RNA - Column Kit

Total RNA - Column Kit

Enzymes & Protein Markers

Restriction Enzymes

General Information

Modifying Enzymes

DNA Polymerases

Ligases / Phosphatases / Kinases

Recombinant Enzymes

Protein Kinases

Buffers and Reagents

Cloning and Mutagenesis

Ligase-free Cloning

Random Mutagenesis Kits

Nucleotides for Random Mutagenesis

Contamination & Controls

Cell Culture Control

Nuclease Detection

Click Chemistry

Click Reagents by Chemistry

Fluorescent Dyes

(Desthio) Biotinylation Reagents

Bifunctional Reagents

Alkyne Reagents

Fluorescent Dyes

Tetrazine Reagents

Fluorescent Dyes

Auxiliary Cu(I) Click Reagents

Fluorescent Dyes

(Desthio) Biotinylation Reagents

Monosaccharides

Click Reagents by Application

Global DNA synthesis monitoring (Cell proliferation)

Enzymatic CLICK-functionalization of DNA

5-hmC detection

Global RNA synthesis monitoring

Analysis of poly(A) tail dynamics (polyadenylation)

Enzymatic CLICK-functionalization of RNA

... on Proteins

Protein synthesis monitoring - Puromycin-based

Protein synthesis monitoring - residue-selective

Choline-containing phospholipid synthesis monitoring

... in Posttranslational Modification Analysis

Phosphorylation

... on Bacteria/Pathogens

LEXSY Expression

LEXSY Configurations

Inducible (Genome integrated)

Inducible (Episomal)

Constitutive (Genome integrated)

In Vitro (cell-free)

Custom Expression

LEXSY Cultivation

Cultivation Kits

Complex LEXSY Cultivation Media

LEXSY Background

LEXSY Selection Guide

Applications and selected Examples

Solubility and Functionality of expressed Proteins

Mammalian-type Glycosylation

Expression of complex oligomeric Proteins

Expression of recombinant Antibodies

Structural Biology: LEXSY Proteins for NMR and X-ray Crystallography

LEXSY in Parasitology

Scientific Literature

IP (Licensing Information)

Conference Presentations

Download Methods

LEXSY Grower's FAQ

Recombinant Proteins

GTP Signal Transduction Proteins

Small GTPases (Ras Superfamily)

Rho/Rac/Cdc42 Family

GEFs (Guanine Nucleotide Exchange Factors)

GTPase Effectors

Protein Prenyl Transferases

GTPase Activity Assay

Viral and Microbial Antigens

Chikungunya Virus

Cytomegalovirus (CMV)

Epstein-Barr Virus (EBV)

Human T-cell Lymphotropic Virus (HTLV)

Rubella Virus (RV)

Tick-Borne Encephalitis Virus (TBEV)

SARS

Varizella-Zoster-Virus (VZV)

West Nile Virus

Recombinant Enzymes

Protein Kinases

Native Proteins

Viral and Microbial Antigens

Bacterial Antigens

Fungal Antigens

Parasitic Antigens

Detection & Analysis

Antioxidant Antibodies

Neurobiology Antibodies

Protein Prenyl Transferases

FTase Substrates and Related Proteins

GGTase-I Substrates and Related Proteins

RabGGTase Substrates and Related Proteins

ATP Binding Proteins

Crystallography & Cryo-EM

Crystal Screens

JBScreen Classic

JBScreen Membrane

JBScreen Kinase

JBScreen Nuc-Pro

JBScreen PEG/Salt

JBScreen Pentaerythritol

JBScreen PACT++

JBScreen JCSG++

JBScreen Wizard

Thermofluor Screens

Additive Screens

Solubility & Stability Screens

JBScreen Thermofluor

Plates & Accessories

SuperClear™ Plates

In-situ-1 Plate

CrystalDirect™ Plate

CrystalQuick™ Plates

CrystalQuick™X Plate

Next Generation CrystalEX™ Microplates

MRC 2-well and 3-well Plates

HDP Hanging Drop Plate

AxyGem™ Plate & Lid

Lipidic Cubic Phase Plates

LCP Glass Sandwich Set

Lipidic Cubic Phase Screening Kit

Microbatch Plates

MRC Under Oil Plate

Vapor Batch Plates

Cover Slides & Grease

96 Well Micro-Dialysis Plate

96 Well Masterblocks & Cap Mats

Crystallization Model Protein

Screening Membrane Proteins

JBScreen Membrane

LCP Lipids & Phospholipids

LCP Glass Sandwich Set

Lipidic Cubic Phase Screening Kit

Chemical Environment

Crystallization Stock Solutions

JBScreen Thermofluor

Thermodynamics / Kinetics

Crystal Dehydration

JBS Beads-for-Seeds

Data Collection

Sample Retrieval and Mounting

Dual-Thickness MicroMounts™ SPINE

Dual-Thickness MicroLoops™ SPINE

Dual-Thickness MicroLoops LD™ SPINE

MicroLoops E™ SPINE

MicroMeshes™ SPINE

Indexed MicroMeshes™ SPINE

MicroGrippers™ SPINE

MicroCrystal Mounts™

Crystallography Sampler Kit™

Sample Manipulation and Measurement

Cryo and Room Temperature Crystallography

Goniometer Bases

Magnetic CryoVials

Mount-Base-Vial Assemblies

Dual-Thickness MicroMount Assembly

MicroMesh Assembly

Dual-Thickness MicroLoop Assembly

Dual-Thickness MicroLoop LD Assembly

MicroLoop E Assembly

MicroGripper Assembly

MicroRT™ Tubing Kit and MicroRT™ Aligner

Oils and Grease

Crystallography Starter Kits

Small Molecule Crystallography Starter Kit™

MicroRT™ Room Temperature Starter Kit

Crystallography Sampler Kit™

Crystal Storage and Shipping

Magnetic CryoVials

Uni-Pucks and Accessories

SPINE Pucks and Accessories

Cryogenic Refrigerators

Cryoware Labels

Base Holders and Cleaning Kit

Goniometer Head Adapter

Tantalum Cluster Derivatization Kit

JBS Tungsten Cluster Derivatization Kits

JBS Magic Triangle

Mercurated and Selenium-containing Nucleotides

Mercurated Nucleotides

Selenium-containing Nucleotides

Quantifoil® Holey Carbon Films with 2 nm Continuous Carbon

Quantifoil® Holey Carbon Films

UltrAuFoil® Holey Gold Films

Quantifoil® Holey SiO2 Films

Other Quantifoil® Films

C-flat™ Holey Carbon Films

Au-flat™ Holey Gold Films

Specimen Storage and Shipping

Cryo-EM Pucks and Accessories

Cryogenic Refrigerators

Probes & Epigenetics

Reactive Components

Reactive Fluorescent Dyes

Reactive Haptens

Azides of Biotin/Desthiobiotin

DBCO-containing Biotinylation Reagents

Bifunctional Reagents

DBCO-(functional group)

Phosphatase Substrates

DNA/cDNA Labeling

Fluorescent DNA/cDNA Labeling

Fluorescent Nucleotides

Fluorescent PCR Labeling Kits

Fluorescent Nick Translation Labeling Kits

Hapten Labeling of DNA/cDNA

Biotinylated Nucleotides

Digoxigenin-/Dinitrophenol-modified Nucleotides

Biotin & Digoxigenin PCR Labeling Kits

Biotin & Digoxigenin Nick Translation Labeling Kits

Biotin & Digoxigenin 3' End Oligonucleotide Labeling Kits

Click Chemistry-based DNA/cDNA Labeling

CLICK-functionalized Nucleotides

Amine Labeling of DNA/cDNA

Amine-modified Nucleotides

LNA Labeling of DNA/cDNA

Enzyme Labeling Reagent Kits

3'-End Oligonucleotide Labeling Reagents

RNA/cRNA Labeling

Fluorescent RNA/cRNA Labeling

Fluorescent Nucleotides

Fluorescent in vitro Transcription Labeling Kits

Hapten Labeling of RNA/cRNA

Biotinylated Nucleotides

Digoxigenin-modified Nucleotides

Hapten in vitro Transcription Labeling Kits

Click Chemistry-based RNA/cRNA Labeling

CLICK-functionalized Nucleotides

CLICK T7 in vitro Transcription Labeling Kits

Amine Labeling of RNA/cRNA

Amine-modified Nucleotides

Protein Labeling

Labeling of Purified Proteins

Fluorescent Amine Labeling

Fluorescent Thiol Labeling

Biotin Amine Labeling

Labeling of Nascent Proteins

ATP dependent Lysine-based Labeling

Amino Acid-based Fluorescent & Biotin Labeling

Puromycin-based Fluorescent & Biotin Labeling

Reporter Protein-based Labeling

dC-Puromycin-based Fluorescent & Biotin Protein Labeling

Fluorescent Hormones

DNA (De)Methylation

Nucleotides & Nucleosides

Restriction Enzymes

5-hmC Detection with UDP-6-Azide-Glucose

5-hmC/5-mC DNA Labeling

RNA (De)Methylation

Nucleotides & Nucleosides

RNA Technologies

Raw materials for mRNA production

Kits for non-modified (m)RNA Synthesis

Kits for nucleoside base-modified mRNA Synthesis

Single components for (m)RNA Synthesis

Kits for dsRNA/RNAi Synthesis

RNA Labeling & Modification

Random RNA Labeling (in vitro Transcription-based)

3'-End RNA Labeling (T4 RNA Ligase 1-based)

RNA-modifying enzymes

RNA Analysis & Detection

Northern Blot probes (non-radioactive)

NMR-based RNA structure determination

RNA Crosslinking

dsRNA detection

Poly (A) carrier RNA-based RNA purification

SELEX/Aptamer Modification

RNA-guided gene targeting

(s)gRNA Synthesis

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